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干細胞生物材料研究組

李文忠

新加坡國立大學(xué)博士、德國干細胞治療臨床轉(zhuǎn)換中心 博士后、柏林再生醫(yī)學(xué)中心德國亥姆霍茲國家研究中心聯(lián)合會生物材料研究所研究員、柏林自由大學(xué)化學(xué)和生物化學(xué)研究所課題組長、溫醫(yī)大眼視光學(xué)院課題組長、博士生導(dǎo)師、浙江省特聘專家，發(fā)表SCI文章70余篇，曾指導(dǎo)德國醫(yī)學(xué)博士2名，博士研究生10余名。

Email: BCRTLWZ@gmail.com

招生專業(yè)

化學(xué)材料，醫(yī)學(xué)，生物學(xué)，生物工程

研究方向

生物醫(yī)學(xué)材料，干細胞組織工程，生物芯片，納米醫(yī)學(xué)，生物材料與干細胞調(diào)控

代表性論著

1. Pan Y, Zhou S, Li Y, Parshad B, Li W*, Haag R. Novel dendritic polyglycerol-conjugated, mesoporous silica-based targeting nanocarriers for co-delivery of doxorubicin and tariquidar to overcome multidrug resistance in breast cancer stem cells. Journal of Controlled Release. 2020 in press IF: 7.90

2. Zhou S, Pan Z, Zhang J, Li Y, Neumann F, Schwerdtle T, Li W*, Haag R. Dendritic polyglycerol-conjugated gold nanostars with different densities of functional groups to regulate osteogenesis from human mesenchymal stem cells. Nanoscale. 2020 in press IF: 6.97

3. Chen J, Yu L, Li Y, Cuellar‐Camacho JL, Chai Y, Li D, Li Y, Liu H, Ou L, Li W*, Haag R. Biospecific monolayer coating for multivalent capture of circulating tumor cells with high sensitivity. Advanced functional materials. 2019; 28: 1808961. IF: 16.83

4. Zhang J, Cheng C, Cuellar-Camacho JL, Li M, Xia Y, Li W*, Haag R. Thermally responsive microfibers mediated stem cell fate via reversibly dynamic mechanical stimulation. Advanced functional materials. 2018; 28: 1804773. IF: 16.83

5. Ren X, Feng Y, Guo J, Wang H, Li Q, Yang J, Hao X, Lv J, Ma N, Li W. Surface modification and endothelialization of biomaterials as potential scaffolds for vascular tissue engineering applications. Chemical Society Reviews. 2015; 44: 5680-5742. IF: 42.84

6. Gaebel R, Ma N, Liu J, Guan J, Koch L, Klopsch C, Gruene M, Toelk A, Wang W, Mark P, Wang F, Chichkov B, Li W*, Steinhoff G. Patterning human stem cells and endothelial cells with laser printing for cardiac regeneration. Biomaterials, 2011; 32: 9218-9230. IF: 10.27

7. Gaebel R, Furlani D, Sorg H, Polchow B, Frank J, Bieback K, Wang W, Klopsch C, Ong L, Li W*, Ma N, Steinhoff G. Cell origin of human mesenchymal stem cells determines a different healing performance in cardiac regeneration. PLoS ONE, 2011; 6: e15652. IF: 4.351

8. Klopsch C, Furlani D, G?belR, Li W*, Ugurlucan M, Kundt G, Zingler C, Titze U, Wang W, Ong L, Wagner K, Li R, Ma N, Steinhoff G. Intracardiac injection of erythropoietin induces stem cell recruitment and improves cardiac functions in a rat myocardial infarction model. Journal of Cellular and Molecular Medicine, 2009; 13: 664-679. IF: 6.81

9. Furlani D, Li W⁺⁺, Pittermann E, Klopsch C, Wang L, Knopp A, Jungebluth P, Thedinga E, Havenstein C, Westien I, Ugurlucan M, Li RK, Ma N, Steinhoff G. A transformed cell population derived from cultured mesenchymal stem cells has no functional effect after transplantation into the injured heart. Cell Transplantation, 2009; 18: 319-331. IF: 5.25

10. Li W, Ma N, Ong LL, Nesselmann C, Klopsch C, Ladilov Y, Furlani D, Piechaczek C, Moebius JM, Lutzow K, Lendlein A, Stamm C, Li RK, Steinhoff G. Bcl-2 engineered MSCs inhibited apoptosis and improved heart function. Stem Cells, 2007; 25: 2118-2127. IF: 11.27